Also, these side effects were primarily observed in younger men, particularly in the 16–39-year-old age group. It is possible that in people who received a different technology for their first dose, and then switched to an mRNA vaccine for their second dose, these people could also experience heart inflammation issues, though more data is needed, de Lemos noted.Īccording to a 10 June CDC presentation detailing US vaccine safety data collected through 31 May, most heart inflammation events were observed after the second dose (573 events) compared with the first dose (216 events). This suggests that myocarditis following mRNA vaccination requires an initial exposure, either from COVID-19 infection itself or from the first dose of an mRNA vaccine, he added. In people who have experienced myocarditis after the first dose, they appear to have previously had COVID-19 infection, Kim noted. Heart inflammation is mainly observed after the second dose, agreed Dr Han Woong Kim, associate professor of medicine, Department of Cardiology, Duke University School of Medicine, Durham, North Carolina.
The risk of myocarditis and pericarditis with mRNA vaccine boosters needs to be monitored closely as it is possible the third dose may lead to an increased frequency of these rare side effects, said Dr James de Lemos, professor of internal medicine, Division of Cardiology, University of Texas Southwestern Medical Center, Dallas. Heart inflammation seen with prior exposure AstraZeneca, Johnson & Johnson and Moderna did not reply to a comment request. Pfizer made headlines this month as it floated to the US and Europe’s regulatory authorities the possibility of an emergency authorization for boosters.Ī Pfizer spokesperson said it will continue to monitor all Comirnaty (BNT162b2) adverse events from clinical trials and from real-world experience. These side effects are unlikely to diminish from public eye with the potential of boosters to be deployed down the line to combat the deleterious efficacy effect of the Delta variant or other future variants on currently authorized vaccines. Initial reports of these rare side effects have grabbed the public’s attention, particularly at a critical point in the US where its robust COVID-19 vaccine uptake in the past few months has stalled due to vaccine hesitancy. Boosters suggested to combat Delta variant
Pfizer booster side effects elevated heart rate download#
Please check your email to download the white paper.Īs for the potential booster use of adenovirus-vectored vaccines from AstraZeneca and Johnson & Johnson, the rare side effect of vaccine-induced thrombosis and thrombocytopenia (VITT) may be an unlikely issue considering it is primarily observed with the first shot of AstraZeneca’s double-dose Vaxzevria (AZD1222).
0 kommentar(er)
